Bioanalysis > Small Molecules

Small Molecules

With particular strength in mass spectrometry and state-of-the-art bioanalytical facilities, Quotient Bioresearch is a leading specialist in the analysis of small molecule drugs and biomarkers in biological fluids.

We have the capability, experience and industry-leading expertise to provide bioanalytical support from discovery through to post-market clinical trials.

We provide you with a complete and flexible project managed service from feasibility studies to sample analysis including study plans, analytical data and reporting and provide a single point of contact and regular project updates with the assurance of quality and accuracy from the very best scientific staff.

We have experience managing clinical programmes for all phases of drug development and molecule types and have particular strengths in:

  • Adopting new methodologies and techniques - Allowing us to give our clients flexible capacity and choice
  • New method development– Extensive experience with a wide range of species, matrices and drug types – from new chemical entities to chiral compounds, generic and over the counter drugs, peptides and comparator drugs.
  • New method validation – Testing and validation methods to OECD and FDA standards. We also have an extensive library of non-proprietary validated methods.
  • Rapid turnaround drug discovery analyses – We can provide a rapid turnaround of non-reg discovery samples with typical method setup and analyses of 5 days.
  • Sample analysis – We offer a rapid sample turnaround service capable of supporting first-in-man studies. We will work to sponsor specific study plans as well as our own, and provide quick and accurate analysis, results, pharmacokinetic metrics and reporting.
  • Quality and management – Our quality is assured to GLP, GCP and cGMP standards. Sample information is managed by Watson™ LIMS. Projects are managed by a single point of contact client manager or study director and monitored by dedicated independent quality assurance personnel.

 

OECD - Organisation for Economic Cooperation and Development; FDA - Food and Drug Administration; GLP - Good Laboratory Practice; GCP - Good Clinical Practice; cGMP - Current Good Manufacturing Practice