Pharmaceutical Sciences
Our comprehensive facilities and expertise allow us to offer you a complete service package for the development, manufacture and release of a wide range of pharmaceutical dosage forms. These include small volume parenterals, tablets, hard gelatin capsules, oral solutions and inhaled products.
We have more than 19 years’ experience of developing oral dosage forms to achieve once- to twice-daily dosing regimens. We use a wide range of modified release formulation strategies to address the physicochemical and biopharmaceutical delivery challenges presented by many new chemical entities. We also support you through the life-cycle management of existing products.
We have facilitated the development of many new and established inhaled drug products and device technologies. We provide you with full support in developing and characterising formulations for new and established drugs. This support continues from the initial formulation concepts through to efficacy testing in patients or healthy volunteers.
Our licensed GMP manufacturing facilities consist of clean rooms, with associated preparation areas, raw material and controlled product storage areas. Grade A isolators provide an environment for the aseptic preparation of injectable formulations. We have an extensive range of pharmaceutical processing equipment for the manufacture of drug products.
Our on-site pharmaceutical analysis capability provides support to your formulation development activities, as well as assisting the QC release of investigational medicinal products (IMPs). We have access to approved sub-contract laboratories for additional analytical techniques, where necessary.
Our significant pharmaceutical sciences experience includes:
- Extensive development experience across a wide range of difficult to formulate drugs.
- Knowledge concerning improvements to solubility, stability and poor bioavailability.
- Drug delivery of small molecules and macromolecules.
- Formulation strategies for modified, sustained and delayed release dosage forms.
- Formulation radiolabelling for gamma scintigraphy studies.
- Rapid development and manufacture of IV dosage forms.
- Development and qualification of analytical test methods.
- Stability testing of investigational medicinal products.
- Rapid manufacture of products for all routes of administration.