Small molecule drugs
With particular strength in mass spectrometry and state-of-the-art bioanalytical facilities, Quotient Bioresearch is a leading specialist in the analysis of small molecule drugs in biological fluids. We have the capability, experience and industry-leading expertise to provide bioanalytical support from discovery through to post-market clinical trials.
We provide a complete, project managed service from feasibility studies to sample analysis including study plans, analytical data and reporting. You get a single point of contact, regular updates and our assurance of quality, accuracy, and the very best scientific expertise.
Our laboratories are equipped with the latest technology including LTQ Orbitrap, UPLC and more than fifty GC and LC mass spectrometry systems.
- Feasibility studies – investigation of sample preparation including liquid-liquid extraction (LLE) and solid phase extraction (SPE), analytical techniques such as liquid chromatography tandem mass spectrometry (LC-MS/MS) and estimates of limits of quantification
- Method development – we have extensive experience with a wide range of species, matrices and drug types – from new chemical entities to chiral compounds, generic and over the counter drugs, peptides and comparator drugs
- Method validation – testing and validation methods to FDA standards – we also have a library of non-proprietary validated methods
- Sample analysis – we offer a rapid sample turnaround, with automated sample handling. We will work to sponsor specific study plans or our own plans, and provide quick and accurate analysis, results and reporting
- Quality and management – our quality is assured to GLP, GCP and cGMP standards. Information is managed by our 21 CFR part 11 compliant Watson™ LIMS. Projects are managed by a single point of contact client manager or study director and monitored by dedicated independent quality assurance personnel.
Contact us for more information and to discuss your specific needs.
Further reading
The following downloads are available as .pdf files, or get in touch for a hard copy.
- Bioanalysis of small molecules – fact sheet with more information about our small molecule services.