Metabolism and Drug Discovery

Quotient Bioresearch provides a range of clinical and non-clinical metabolism services to support absorption, distribution, metabolism and excretion (ADME) studies for candidate pharmaceuticals. This work forms a vital part of the regulatory process.

Regulatory DMPK

We can provide a complete regulatory DMPK service.

Human Metabolism

Working with specialist clinical research facilities we offer a complete clinical metabolism and pharmacokinetic service including - as with all our services - the best in project management and reporting.

In vitro Metabolism 

From stability screening to drug-drug interactions and studies designed for your specific needs.

Metabolite Identification 

Using our highly experienced staff and state-of-the-art MS/MS equipment we are able to provide informed evaluation on metabolite profiling and identification.

Discovery Support 

A range of in vitro, bioanalysis and pharmacokinetic techniques to support drug discovery - including a variety of candidate selection study options and bespoke studies.  

Dermal Penetration 

Measuring dermal absorption requires specialist equipment and the experience to design studies to get the best results. We work to international guidelines to provide you accurate answers for a range of dermal penetration questions.

Agrochemical and Chemical Development 

Senior staff at Quotient Bioresearch have over 20 years experience in studies designed to support agrochemical and chemical registration programmes, and are designed to  meet requirements of the regulatory authorities worldwide.

Contact us for more information or to discuss your specific needs

ADME - Absorption, Distribution, Metabolism and Excretion; DMPK - Drug Metabolism and Pharmacokinetics; MS - Mass Spectrometry.